This paper raises an open critical discussion on some key notions in Michael Ruse’s philosophy. These include the conceptual elements of scientific explanation, the difference between epistemic and cultural values, the epistemological status of science and religion in explaining nature, the compatibility or incompatibility between Darwinian thought and Christian thought, and especially between evolutionary theory and creationism, the key importance of admitting or not admitting supernatural causality when qualifying an explanation as scientific, the role played by the divinity in the (...) argumentation about the compatibility or incompatibility between science and religion, the convenience of not understanding the Abrahamic god from an ontological perspective but from a psychological one, etc. It ends by proposing certain conclusions that could perhaps contribute to contrast and enrich his philosophy. (shrink)